Signed from Anderlecht for £13 million this summer, the 20-year-old forward started for the first time away to Manchester United on Saturday.
Now Steve McClaren may look to get him off the mark in terms of goals against League Two opposition when the Cobblers visit St James' Park on Tuesday night.
Guilty of taking cup games lightly in recent years, the Magpies mindset may change under their new manager, well aware of the boost to his own reputation that a good run will bring.
Fellow new arrivals Karl Darlow and Jamaal Lascelles, signed from Nottingham Forest, may also start for the Premier League side while the interesting story from a Northampton point of view would be the involvement of Ivan Toney just weeks after he left Sixfields.
A stronger Newcastle side would lessen Town's chances of causing an upset of course but would hopefully add to the atmosphere and attendance on the night.