Saturday's meeting at Sixfields will be the 37th between the two teams and Rotherham just slightly have the upper hand.
They have won 16 of the 36 games played to date with Northampton coming out on top 13 times.
Both games last season ended in 2-2 draws.
Check out the Cobblers' head-to-head record against the Millers or any other side by clicking below.