Diego De Girolamo is expected to feature for Northampton against Luton despite international duty with Italy under-20s
The on-loan Sheffield United striker was due to play against Switzerland in Lecco on Thursday before flying back.
Lewis Hornby played in a 2-1 reserve-team win over MK Dons on Monday as he recovers from a long-term back injury
The midfielder, who has not featured for the Cobblers since the 2013 play-off final defeat to Bradford, played the final 20 minutes.
Luton will make the short trip without injured pair Elliot Lee (hip) and Fraser Franks (ankle).
Both players picked up knocks in Tuesday's home defeat by Wycombe and will be big losses to a Hatters outfit on a five-game losing streak.
First-choice goalkeeper Mark Tyler remains unavailable so Elliot Justham will continue to deputise, but Jonathan Smith is set to return after missing the last three matches.
John Still's men have picked up just three points out of a possible 18, a run which has left them just one point above eighth-placed Plymouth
Source : PA
Source: PA