Aidy Boothroyd will not be too disappointed at having another clear week to work with his team and build on the encouraging results of Town's last two games, a goalless draw against MOrecambe and the away victory at AFC Wimbledon.
Oxford's clash with Pompey gives them the chance to improve on some poor home form with Saturday's defeat at the hands of Southend United their latest bad result at the Kassam Stadium.
Summer signing Josh Ruffels is set to make his debut in midfield as manager Chris Wilder weighs up potential changes for the visit of the Cobblers.
***Update*** Oxford were beaten 2-1 by Pompey with James Constable getting the home goal. The U's are expected to have Dave Kitson, Andy Whing and captain Jake Wright available again at the weekend.