Midfielder JJ Melligan (hamstring) is definitely out, while fellow midfielder Frankie Artus could return next week.
Northampton defender Dean Beckwith may be back after missing the last five games with a thigh problem.
Striker Courtney Herbert has a calf injury and will be out for three weeks, but defender Marcus Hall is fit following a hamstring problem.
Northampton Town manager Ian Sampson told BBC Look East: "We have got to stay positive and keep the decent performances going.
"There's no logic as to why we can play so well in the Cup and not turn that into results in the League."
Source: BBC Sport
Source: BBC Sport