Northampton will find out their opening opponents at 10:00am, a season after their unforgettable run in the competition.
Ian Sampson's side saw off Brighton & Hove Albion, who ended up as champions of League One, in the opening round thanks to goals from Jacobs and McKay.
Then a dramatic 3-3 draw at Reading, play-off finalists in the Championship, ended with the Cobblers winning 4-2 on penalties to set up a tie with Liverpool.
And Anfield was left stunned as Northampton once again raised their game to earn a draw in normal time and win through in the shoot-out before the run came to an end at Ipswich.